49ers QB Nick Mullens at QB for injured Jimmy Garoppolo

San Francisco 49ers coach Kyle Shanahan confirmed Friday what he’s hinted at all week: Nick Mullens will start at quarterback in substitution of the injured Jimmy Garoppolo on Sunday versus the New York Giants.

Shanahan stated Wednesday that Mullens would “most likely” start in place of Garoppolo, who is dealing with a high right ankle sprain, but he made it official Friday on KNBR radio in San Francisco. Shanahan told “The Murph and Mac Show” that Mullens will start for Garoppolo and that Garoppolo will not be active for the game, leaving C.J. Beathard as Mullens’ backup.

Mullens will be making his first start since Dec. 30, 2018, which was the final appearance in an eight-game stretch for him as the starter after Garoppolo tore his left ACL in Week 3 of that campaign. He threw for 2,277 yards with 13 touchdowns and 10 interceptions and had a passer rating of 90.8 as the Niners went 3-5 in his starts.

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Early in the week, the Niners had expressed some positivity that Garoppolo could play, but it became apparent by Wednesday that it was unlikely. Garoppolo suffered the ankle injury in the first quarter of last week’s win versus the New York Jets and played through it before being removed from the game at halftime.

Mullens ended the game, going 8-of-11 for 71 yards with an interception as the 49ers rolled to a 31-13 win.

During training at The Greenbrier Resort in White Sulphur Springs, West Virginia, this week, Mullens has taken on the role of starter in practice, with Beathard as the backup.

Garoppolo did not practice Wednesday or Thursday and is not expected to on Friday.

“He’s locked in,” tight end George Kittle stated Thursday about Mullens. “He’s got the game plan down, he’s got a rocket for an arm, he’s slinging it, he’s confident. And I know he’s just excited to get the opportunity to play. If he gets to play, I know he’s going to take advantage of that situation because that dude loves football.

He’s going to give it his all, so we’re definitely in good hands if Jimmy can’t go.” “I’m very confident in Jet,” Shanahan said Wednesday. “He’s done a great job in all the reps that he’s gotten in these two weeks.

Every time he’s gotten opportunities, he came through for us. Obviously, with those two guys being out, he should get more opportunities this week and he deserves it. I know he’s excited for it and we’re excited to see him.”

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